Nutritional Outlook

Nutritional Outlook, May 2018

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NUTRITIONAL OUTLOOK ■ MAY 2018 branded Litesse Ultra polydextrose f ber—with controlling body fat mass, core fat mass, waist circumference, and calorie intake in overweight and obese adults. Subjects supplementing with the probiotic/f ber combination had 4.5% less total body fat mass, 6.7% less trunk fat, and a 2.6-cm/1.02-in. smaller waist circumference af- ter six months of supplementation relative to the placebo. T e supplement's mechanism of action appears to relate to im- provements in intestinal integrity, as well as anti-inf ammatory ef ects and, potentially, benef cial changes to the gut microbiota's composition. "Moreover," Maukonen says, "the unique results were obtained with no changes to diet or exercise habits. And there were no stimulants added, so participants felt like themselves while con- trolling body fat mass and improving body composition." Bye to the Bad Old Days Going forward, clinically substantiated evidence like this will be- come more important than ever. As Appell says, "Science on ef cacy and safety drive the market by keeping consumers both realistic and optimistic. T ey want to know how their supplements work and what they can expect. Sound research and messaging that's easy to understand help them gain the knowledge they need to make edu- cated purchases." In other words, "Gone are the days of 'magic bullet' pills boasting unfounded claims or using questionable ingredients with potential side ef ects," he says. Weight management has undergone a much- needed market correction as manufacturers lean less on sensation- alism and more on real, live ef ects, he adds, and "that can only lead to better formulas that can prosper in this growing market." References 1. Hales CM et al., "Trends in obesity and severe obesity prevalence in US youth and adults by sex and age, 2007-2008 to 2015-2016," JAMA. Published online March 23, 2018. 2. Haslam DW et al., "Obesity," The Lancet, vol. 366, no. 9492 (October 1, 2005): 1197- 1209 3. Kolotkin RL et al., "A systematic review of reviews: exploring the relationship be- tween obesity, weight loss and health-related quality of life," Clinical Obesity, vol. 7, no. 5 (October 2017): 273-289 4. "Obesity Rates and Trends." T e State of Obesity, Accessed March 2018. 5. Fallah-Fini S et al., "T e additional costs and health ef ects of a patient having overweight or obesity: a computational model," Obesity, vol. 25, no. 10 (September 26, 2017): 1809-1815 6. "Impact of Sugar Concern on Consumption Behavior: What We Say vs. What We Do." NPD Group report. September 2017. 7. OmniActive Insights Program, December 27, 2017; 500 respondents. 8. Hao L et al., "Appetite and gut hormones response to a putative α-glucosidase in- hibitor, Salacia chinensis, in overweight/obese adults: a double blind randomized controlled trial," Nutrients, vol. 9, no. 8 (August 12, 2017): 869 9. Grube et al., "Weight reduction and maintenance with IQP-PV-101: a 12-week randomized controlled study with a 24-week open label period," Obesity, vol. 22, no. 3 (March 2014): 645-651 10. Udani JK et al., "A proprietary alpha-amylase inhibitor from white bean (Phaseo- lus vulgaris): a review of clinical studies on weight loss and glycemic control," Nu- trition Journal. Published online March 17, 2011. 11. Stenman et al., "Probiotic with or without f ber controls body fat mass, associ- ated with serum zonulin, in overweight and obese adults-randomized controlled trial," EBioMedicine. Published online October 26, 2016. Kimberly J. Decker writes for the food and nutrition industries from her base in the San Francisco area, where she enjoys eating food as much as she does writing about it. > 98% pure trans-resveratrol from fermentation made like no other Bone health Cardiovascular health Blood glucose Cognitive health Oral health Beauty from within

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