Nutritional Outlook

Nutritional Outlook, September 2013

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Alzheimer's disease compared to placebo, other investigations of ginkgo in patients with dementia have shown signifcant benefts. A recently published review by Ralf Ihl from University of Dusseldorf, Germany, on four recent trials investigating Ginkgo biloba extract EGb 761 in 1294 patients with dementia, found that ginkgo supplementation improved cognitive performance, behavioral symptoms, and measures of daily living activities compared to placebo (International Journal of Psychiatry in Clinical Practice, 2013). Flavanols from cocoa have also been investigated for improving cognitive function in individuals with mild cognitive impairment. A review article by Alexander Sokolov's group from the University of Tübingen Medical School in Germany highlights the potential cognitive and behavioral benefts associated with the consumption of cocoa favanols in humans and discusses their Connect. Discover. Collaborate. potential mechanisms of neuroprotection and neuromodulation (Neuroscience and Biobehavioral Reviews, 2013). Additionally, Giovambattista Desideri and colleagues from the University of L'Aquila in Italy conducted the Cocoa, Cognition, and Aging (CoCoA) Study in 90 elderly patients with mild cognitive impairment (Hypertension, 2012). For eight weeks, subjects consumed a daily drink containing favanols at a high dose (990 mg/day favanols), medium dose (520 mg/day), or low dose (45 mg/day). While scores on the Mini Mental State Examination, a measure of cognitive function, were similar in all groups at the end of the study, subjects in the high and medium favanol groups showed improvements in other cognitive measures compared to the low favanol group. Verbal fuency and scores on the Trail Making Test, a standardized assessment of visual attention and cognitive fexibility, both improved. October 15Ð16, 2013 Continued research into the benefts of various favonoids will serve to further clarify their overall impact on cognitive impairment, dementia, and other neurodegenerative conditions. Given the broad nature of their interactions with brain cells and the vascular system, it is clear that increased favonoid consumption as a dietary and supplementary intervention holds signifcant potential for reduced risk of age-related cognitive dysfunction. As the prevalence of these diseases and their burden to society increases, continuing to explore efective means to prevent or delay their onset is of paramount importance. October 29Ð30, 2013 Reliant Center Houston, TX Minneapolis Convention Center Minneapolis, MN April 15Ð16, 2014 Meet Top Suppliers, Find New Technologies, and Innovate Your Packaging. Irfan Qureshi, ND, is chief regulatory ofcer for Vitamin Research Products LLC. His current focus includes oversight of product development, regulatory afairs, quality control, and quality assurance. June 10Ð11, 2014 Charlotte Convention Center Charlotte, NC Palais des congrès de Montréal Montréal, QC Anaheim Convention Center Anaheim, CA June 10Ð12, 2014 Jacob K. Javits Convention Center New York, NY November 19Ð20, 2014 February 11Ð13, 2014 Jacob K. Javits Convention Center New York, NY May 19Ð21, 2015 Toronto Congress Centre Toronto, ON For details on exhibiting or attending, please visit 26142_AS_PK13 NUTRITIONAL OUTLOOK magenta cyan yellow black ■ 39 SEPTEMBER 2013 ES315729_NO1309_c39.pgs 09.04.2013 04:17 UBM

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